INSL3

Across TCGA patient cohorts, INSL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,210 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INSL3-associated proteins across cancer lineages are SH3BGRL3, STAT5A, and THEMIS2. Each is linked with INSL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both INSL3-to-partner and partner-to-INSL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INSL3 versus SH3BGRL3 in PDAC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INSL3→partner) and Y-score (partner→INSL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SH3BGRL3 →	+0.435	+0.401	<.001	.002	3	5
BRCA	STAT5A →	+0.306	+0.381	.001	.001	3	5
GBM	THEMIS2 →	+0.423	+0.231	<.001	<.001	3	4
GBM	TRIM38 →	+0.414	+0.192	.001	.005	3	4
LSCC	PSMB10 →	+0.483	+0.547	<.001	<.001	3	4
PDAC	PSMB8 →	+0.286	+0.375	<.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,210 associations by consensus.

INSL3 vs SH3BGRL3 — PDAC

Explore this scatter interactively →