INPP5K

Across TCGA patient cohorts, INPP5K RNA expression is significantly associated with the protein abundance of many other proteins, with 9,899 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible INPP5K-associated proteins across cancer lineages are YWHAE, PAFAH1B1, and CRK. Each is linked with INPP5K in more than 7 cancer types. Because this analysis shows association rather than direction, both INPP5K-to-partner and partner-to-INPP5K results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP5K versus YWHAE in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5K→partner) and Y-score (partner→INPP5K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YWHAE →	+0.283	+0.410	<.001	<.001	3	8
OV	PAFAH1B1 →	+0.351	+0.716	<.001	<.001	3	7
BRCA	CRK →	+0.231	+0.419	<.001	<.001	3	7
OV	METTL16 →	+0.385	+0.535	<.001	.003	3	6
LSCC	PPIB →	-0.285	-0.408	<.001	<.001	3	6
OV	PITPNA →	+0.311	+0.490	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,899 associations by consensus.

INPP5K vs YWHAE — BRCA

Explore this scatter interactively →