INPP5K

Across TCGA cell cohorts, INPP5K RNA expression is significantly associated with the go_rna of many other GO terms, with 3,670 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INPP5K-associated GO terms across cancer lineages are Regulation of dephosphorylation, Negative regulation of glycogen biosynthetic process, and Endosomal transport. Each is linked with INPP5K in more than 18 cancer types. Because this analysis shows association rather than direction, both INPP5K-to-partner and partner-to-INPP5K results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of dephosphorylation grouped by INPP5K-low versus INPP5K-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5K→partner) and Y-score (partner→INPP5K) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of dephosphorylation →	+0.134	+1.080	<.001	<.001	3	19
LUNG_SCLC	Negative regulation of glycogen biosynthetic process →	+0.227	+0.839	<.001	<.001	3	16
OVARY	Endosomal transport →	+0.056	+0.905	<.001	.006	3	15
KIDNEY	Cytosolic transport →	+0.070	+0.809	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of dephosphorylation →	+0.136	+0.986	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Process utilizing autophagic mechanism →	+0.083	+0.965	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,670 associations by consensus.

Regulation of dephosphorylation by INPP5K expression — OESOPHAGUS

Explore this box plot interactively →