Across TCGA pan-cancer cohorts, INPP5J mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated INPP5J data layer compared with 26 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher INPP5J mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated INPP5J expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, GBM, and LSCC are the cancer types where INPP5J mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.920	0.672	.013	14	view →
GBM	DFS	Tertile	All	0.279	0.547	.040	2	view →
LSCC	DFS	Median	All	0.920	0.630	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: INPP5J tumor-vs-normal RNA expression · all INPP5J data types