INPP5E

Across TCGA cell cohorts, INPP5E RNA expression is significantly associated with the go_rna of many other GO terms, with 4,387 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INPP5E-associated GO terms across cancer lineages are CTP salvage, Metaphase/anaphase transition of cell cycle, and Establishment of RNA localization. Each is linked with INPP5E in more than 17 cancer types. Because this analysis shows association rather than direction, both INPP5E-to-partner and partner-to-INPP5E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by INPP5E-low versus INPP5E-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5E→partner) and Y-score (partner→INPP5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CTP salvage →	+0.175	+0.870	.003	.002	3	18
BONE	Metaphase/anaphase transition of cell cycle →	+0.196	+1.116	<.001	<.001	3	17
OESOPHAGUS	Establishment of RNA localization →	+0.113	+0.685	<.001	.001	3	16
BREAST	Protein depolymerization →	+0.121	+0.834	<.001	<.001	3	16
BONE	Anaphase-promoting complex-dependent catabolic process →	+0.109	+1.113	<.001	<.001	3	16
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.193	+1.021	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,387 associations by consensus.

CTP salvage by INPP5E expression — STOMACH

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