INPP5D

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INPP5D protein abundance is significantly associated with the RNA expression of many other genes, with 19,271 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INPP5D-associated genes across cancer lineages are GPR31, CYTH4, and APOBEC3H. Each is linked with INPP5D in more than 8 cancer types. Because this analysis shows association rather than direction, both INPP5D-to-partner and partner-to-INPP5D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP5D versus GPR31 in CCRCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5D→partner) and Y-score (partner→INPP5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCGPR31 →+0.293+0.285<.001<.00139
GBMCYTH4 →+1.114+0.750<.001<.00139
LUADAPOBEC3H →+0.830+0.364<.001<.00139
HNSCGRAP2 →+0.878+0.491<.001<.00139
GBMNCF4 →+1.203+0.769<.001<.00139
HNSCCSF2RB →+1.238+0.734<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,271 associations by consensus.

INPP5D vs GPR31 — CCRCC

Per-sample scatter of INPP5D vs GPR31 in CCRCC (Pearson r = 0.60).

Explore this scatter interactively →

Exploration