INPP5D

Across TCGA cell cohorts, INPP5D RNA expression is significantly associated with the go_rna of many other GO terms, with 2,871 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INPP5D-associated GO terms across cancer lineages are Lipid translocation, Negative regulation of vascular associated smooth muscle cell proliferation, and Cellular response to cell-matrix adhesion. Each is linked with INPP5D in more than 7 cancer types. Because this analysis shows association rather than direction, both INPP5D-to-partner and partner-to-INPP5D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid translocation grouped by INPP5D-low versus INPP5D-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5D→partner) and Y-score (partner→INPP5D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Lipid translocation →	+0.059	+1.872	.001	<.001	3	8
STOMACH	Negative regulation of vascular associated smooth muscle cell proliferation →	+0.167	+1.352	.001	.002	3	7
SKIN	Cellular response to cell-matrix adhesion →	+0.195	+0.412	<.001	.005	3	6
LARGE_INTESTINE	Cilium or flagellum-dependent cell motility →	-0.050	-1.668	.004	.001	3	6
BLOOD_Lymphoma	Serotonin secretion →	+1.006	+1.185	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Cellular response to phorbol 13-acetate 12-myristate →	+0.177	+0.996	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,871 associations by consensus.

Lipid translocation by INPP5D expression — LARGE_INTESTINE

Explore this box plot interactively →