INPP4B

Across TCGA cell cohorts, INPP4B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,211 significant associations in total. BONE shows the largest number of these associations.

The most reproducible INPP4B-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Positive regulation of proteolysis, and Membrane assembly. Each is linked with INPP4B in more than 13 cancer types. Because this analysis shows association rather than direction, both INPP4B-to-partner and partner-to-INPP4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament polymerization grouped by INPP4B-low versus INPP4B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP4B→partner) and Y-score (partner→INPP4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of actin filament polymerization →	+0.224	+1.911	<.001	<.001	3	14
PANCREAS	Positive regulation of proteolysis →	+0.119	+1.995	<.001	<.001	2	13
PANCREAS	Membrane assembly →	+0.108	+1.696	<.001	<.001	3	12
BONE	Regulation of proteolysis →	+0.109	+1.477	<.001	<.001	3	11
BONE	Regulation of body fluid levels →	+0.091	+1.638	<.001	<.001	3	11
PANCREAS	Negative regulation of cell-cell adhesion →	+0.094	+1.631	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,211 associations by consensus.

Negative regulation of actin filament polymerization by INPP4B expression — PANCREAS

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