INPP4A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INPP4A protein abundance is significantly associated with the RNA expression of many other genes, with 21,711 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INPP4A-associated genes across cancer lineages are TESPA1, GRAP2, and BIN2. Each is linked with INPP4A in more than 8 cancer types. Because this analysis shows association rather than direction, both INPP4A-to-partner and partner-to-INPP4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPP4A versus TESPA1 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP4A→partner) and Y-score (partner→INPP4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATESPA1 →+0.953+0.245<.001<.00139
HNSCGRAP2 →+0.839+0.166<.001<.00138
BRCABIN2 →+1.050+0.300<.001<.00138
LSCCLY9 →+0.904+0.219<.001<.00138
GBMCAMK4 →+0.793+0.182.003.00638
LSCCCCR5 →+0.904+0.244<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 21,711 associations by consensus.

INPP4A vs TESPA1 — BRCA

Per-sample scatter of INPP4A vs TESPA1 in BRCA (Pearson r = 0.42).

Explore this scatter interactively →

Exploration