INO80

Across TCGA patient cohorts, INO80 protein abundance is significantly associated with the RNA expression of many other genes, with 9,343 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible INO80-associated genes across cancer lineages are SERTM1, VCPKMT, and SOCS4. Each is linked with INO80 in more than 2 cancer types. Because this analysis shows association rather than direction, both INO80-to-partner and partner-to-INO80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INO80 versus SERTM1 in OV, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80→partner) and Y-score (partner→INO80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SERTM1 →	-0.980	-0.252	.005	.006	3	3
UCEC	VCPKMT →	+0.506	+0.235	.004	<.001	3	3
LSCC	SOCS4 →	+0.431	+0.159	<.001	.001	3	3
LSCC	LIN52 →	+0.400	+0.184	.001	<.001	3	3
UCEC	GPATCH2L →	+0.286	+0.218	.006	<.001	3	3
BRCA	METTL17 →	+0.443	+0.284	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,343 associations by consensus.

INO80 vs SERTM1 — OV

Explore this scatter interactively →