INO80

Across TCGA patient cohorts, INO80 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,640 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INO80-associated proteins across cancer lineages are CAPNS1, TRRAP, and NIPBL. Each is linked with INO80 in more than 5 cancer types. Because this analysis shows association rather than direction, both INO80-to-partner and partner-to-INO80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INO80 versus CAPNS1 in PDAC, with a Pearson correlation of -0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INO80→partner) and Y-score (partner→INO80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CAPNS1 →	-0.456	-0.399	<.001	<.001	3	6
GBM	TRRAP →	+0.241	+0.299	<.001	<.001	3	6
GBM	NIPBL →	+0.264	+0.384	<.001	<.001	3	6
COAD	TXN2 →	-0.807	-1.046	.001	.001	3	5
BRCA	MPHOSPH8_S392 →	+1.216	+0.469	<.001	<.001	3	5
LSCC	AQR →	+0.311	+0.141	<.001	.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,640 associations by consensus.

INO80 vs CAPNS1 — PDAC

Explore this scatter interactively →