INMT

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INMT mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible INMT-associated genes across cancer lineages are Pericytes. Each is linked with INMT in more than 1 cancer types. Because this analysis shows association rather than direction, both INMT-to-partner and partner-to-INMT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pericytes grouped by INMT-low versus INMT-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INMT→partner) and Y-score (partner→INMT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAPericytes →+0.040+3.356.003.04132
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Pericytes by INMT expression — BRCA

Box plot of Pericytes in INMT-low vs INMT-high samples in BRCA.

Explore this box plot interactively →

Exploration