Across TCGA patient cohorts, INKA1 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INKA1-associated genes across cancer lineages are IGHVIII-22-2, MIR4305, and MIR3611. Each is linked with INKA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INKA1-to-partner and partner-to-INKA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INKA1→partner) and Y-score (partner→INKA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	IGHVIII-22-2 →	+2.085	+5.588	<.001	.004	3	1
BLCA	MIR4305 →	+0.332	+5.177	.007	.007	3	1
BLCA	MIR3611 →	+0.543	+5.497	<.001	.004	3	1
BLCA	MIR5580 →	+0.524	+5.106	<.001	.008	3	1
BLCA	SMIM12P1 →	+0.151	+6.618	<.001	.001	3	1
COAD	RNY3P2 →	+0.876	+5.790	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

INKA1 survival (RNA) · tumor vs normal (RNA) · all INKA1 data types