INIP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INIP protein abundance is significantly associated with the RNA expression of many other genes, with 11,942 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INIP-associated genes across cancer lineages are ZBTB26, RMI1, and SEPTIN14P12. Each is linked with INIP in more than 4 cancer types. Because this analysis shows association rather than direction, both INIP-to-partner and partner-to-INIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INIP versus ZBTB26 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INIP→partner) and Y-score (partner→INIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCZBTB26 →+0.475+0.199.006.00135
LSCCRMI1 →+0.797+0.239<.001<.00135
UCECSEPTIN14P12 →+0.939+0.205<.001.00435
LSCCHDGF →+0.601+0.198<.001<.00135
LSCCTMEM97 →+0.887+0.169<.001<.00134
BRCALTBP2 →-0.810-0.262.004<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,942 associations by consensus.

INIP vs ZBTB26 — HNSC

Per-sample scatter of INIP vs ZBTB26 in HNSC (Pearson r = 0.28).

Explore this scatter interactively →

Exploration