INIP

Across TCGA patient cohorts, INIP mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INIP-associated genes across cancer lineages are RN7SL332P, RNY1P2, and MIR6870. Each is linked with INIP in more than 1 cancer types. Because this analysis shows association rather than direction, both INIP-to-partner and partner-to-INIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL332P grouped by INIP-low versus INIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INIP→partner) and Y-score (partner→INIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL332P →	+0.308	+4.868	<.001	.004	3	2
SKCM	RNY1P2 →	+0.233	+7.816	<.001	.008	3	2
UCEC	MIR6870 →	+0.825	+4.344	<.001	.002	3	1
COAD	ATF1P1 →	+0.228	+6.392	.003	.001	3	1
COAD	H3P9 →	+0.429	+5.602	<.001	.004	3	1
COAD	MTND3P13 →	+0.255	+5.893	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

RN7SL332P by INIP expression — UCEC

Explore this box plot interactively →