INIP

Across TCGA cell cohorts, INIP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,717 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INIP-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Regulation of chromosome condensation, and Positive regulation of chromosome condensation. Each is linked with INIP in more than 18 cancer types. Because this analysis shows association rather than direction, both INIP-to-partner and partner-to-INIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by INIP-low versus INIP-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INIP→partner) and Y-score (partner→INIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Immunoglobulin heavy chain V-D-J recombination →	+0.167	+0.915	.001	.001	3	19
SOFT_TISSUE	Regulation of chromosome condensation →	+0.213	+0.804	<.001	<.001	3	17
PANCREAS	Positive regulation of chromosome condensation →	+0.207	+0.840	<.001	<.001	3	16
PANCREAS	Negative regulation of G2/M transition of mitotic cell cycle →	+0.082	+0.787	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle G2/M phase transition →	+0.094	+1.152	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Interstrand cross-link repair →	+0.090	+0.890	<.001	.002	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,717 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by INIP expression — BLOOD_Myeloma

Explore this box plot interactively →