INHCAP

Across TCGA pan-cancer cohorts, INHCAP RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated INHCAP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher INHCAP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated INHCAP expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

KIRC, KICH, and HNSC are the cancer types where INHCAP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.534	0.705	<.001	79	view →
KICH	DFS	Median	All	0.790	1.000	.004	37	view →
HNSC	OS	Tertile	All	0.819	0.703	.011	35	view →
CESC	OS	Median	All	0.859	0.737	.007	28	view →
PRAD	DFS	Tertile	All	0.828	0.941	<.001	26	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	21	view →
LGG	OS	Tertile	All	0.955	0.843	<.001	17	view →
UCS	OS	Median	III,IV	0.544	0.212	.011	16	view →
LUAD	OS	Median	II,III,IV	0.557	0.352	.020	11	view →
SKCM	OS	Median	All	0.381	0.227	.006	10	view →
LIHC	OS	Quartile	II,III,IV	0.476	0.730	.013	10	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.353	.022	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

INHCAP–KIRC (DFS)

Open the KIRC breakdown →