inhibitor of carbonic anhydrase pseudogeneGenealiases: TFP · TFP1
Q-omics provides the consensus-scored INHCAP profile across patient tissues and cancer cell-line models. INHCAP expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, INHCAP is differentially expressed in 9, with the highest sampling consensus in BRCA. Additionally, INHCAP RNA expression shows 17,734 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, BRCA, and THYM as cancer lineages where INHCAP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for INHCAP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes INHCAP survival associations across molecular data types. INHCAP RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible INHCAP RNA expression–survival associations across cancer types. High INHCAP expression shows unfavorable associations in KIRC, KICH, PRAD and CHOL, but favorable associations in HNSC and CESC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for INHCAP RNA expression.
This table summarizes INHCAP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for INHCAP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. INHCAP shows lower tumor expression in BRCA, KICH, THCA, LUAD and KIRP and higher tumor expression in HNSC. The BRCA box plot shows higher INHCAP RNA expression in normal versus tumor tissue (log2 FC = −0.280, t-test p < 0.001).
This table shows molecular features associated with INHCAP in patient tissues and cancer cell lines. In patient samples, INHCAP shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
