INHBE

Across TCGA patient cohorts, INHBE mutation is significantly associated with the RNA expression of many other genes, with 2,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INHBE-associated genes across cancer lineages are RNA5SP411, MIR633, and RNA5SP412. Each is linked with INHBE in more than 2 cancer types. Because this analysis shows association rather than direction, both INHBE-to-partner and partner-to-INHBE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by INHBE-low versus INHBE-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBE→partner) and Y-score (partner→INHBE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+0.738	+1.808	.007	.007	3	3
BLCA	MIR633 →	+0.389	+4.433	<.001	.007	3	3
UCEC	RNA5SP412 →	+0.602	+2.074	<.001	.004	3	2
BLCA	RNU6-918P →	+0.376	+3.926	<.001	.005	3	2
SKCM	RN7SL303P →	+0.102	+3.302	<.001	.009	3	2
UCEC	SHMT1P1 →	+0.134	+2.545	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,041 associations by consensus.

RNA5SP411 by INHBE expression — UCEC

Explore this box plot interactively →