INHBB

Across TCGA cell cohorts, INHBB mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INHBB-associated genes across cancer lineages are MYH1, C3orf85, and FTHL17. Each is linked with INHBB in more than 1 cancer types. Because this analysis shows association rather than direction, both INHBB-to-partner and partner-to-INHBB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH1 grouped by INHBB-low versus INHBB-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INHBB→partner) and Y-score (partner→INHBB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MYH1 →	+0.022	+5.000	<.001	.006	3	1
PANCREAS	C3orf85 →	+0.132	+5.000	<.001	.006	3	1
BLOOD_Lymphoma	FTHL17 →	+0.180	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	KLHL40 →	+0.006	+5.209	.006	.005	3	1
BLOOD_Lymphoma	S100G →	+0.058	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

MYH1 by INHBB expression — PANCREAS

Explore this box plot interactively →