INGX

Across TCGA pan-cancer cohorts, INGX RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of INGX’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where INGX RNA is more highly expressed in tumor relative to normal tissue. In most cancer types INGX is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

LIHC, LUAD, and HNSC are the cancer types where INGX tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in INGX RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.074	<.001	6	view →
LUAD	All	All	+0.104	.005	4	view →
HNSC	All	All	+0.088	.013	4	view →
THCA	Female	II,III,IV	−0.071	.007	4	view →
KIRP	All	III,IV	+0.088	.034	3	view →
CHOL	All	All	+0.235	.002	2	view →
BRCA	All	III,IV	−0.121	<.001	2	view →
LUSC	All	II,III,IV	+0.090	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

INGX–LIHC

Open the LIHC breakdown →