inhibitor of growth family, X-linked (pseudogene)Genealiases: ING1-like · ING2
Q-omics provides the consensus-scored INGX profile across patient tissues and cancer cell-line models. INGX expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, INGX is differentially expressed in 8, with the highest sampling consensus in LIHC. Additionally, INGX RNA expression shows 9,233 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, LIHC, and THYM as cancer lineages where INGX shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for INGX — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes INGX survival associations across molecular data types. INGX RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible INGX RNA expression–survival associations across cancer types. High INGX expression shows unfavorable associations in COAD, KIRC, ACC, ESCA and LGG, but favorable associations in LUAD. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for INGX RNA expression.
This table summarizes INGX tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in LIHC for RNA.
This table ranks reproducible tumor–normal expression differences for INGX. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. INGX shows lower tumor expression in THCA and higher tumor expression in LIHC, LUAD, HNSC, KIRP and CHOL. The LIHC box plot shows higher INGX RNA expression in tumor versus normal tissue (log2 FC = +0.074, t-test p < 0.001).
This table shows molecular features associated with INGX in patient tissues and cancer cell lines. In patient samples, INGX shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
