ING4

Across TCGA cell cohorts, ING4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,973 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ING4-associated GO terms across cancer lineages are Sperm motility, DNA replication-dependent chromatin disassembly, and Regulation of organelle assembly. Each is linked with ING4 in more than 14 cancer types. Because this analysis shows association rather than direction, both ING4-to-partner and partner-to-ING4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by ING4-low versus ING4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ING4→partner) and Y-score (partner→ING4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.131	-1.629	<.001	<.001	3	14
BONE	DNA replication-dependent chromatin disassembly →	+0.167	+1.090	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of organelle assembly →	+0.040	+0.980	<.001	.004	2	15
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.131	-1.629	<.001	<.001	3	14
LARGE_INTESTINE	Regulation of macroautophagy →	+0.040	+0.841	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.049	+1.081	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,973 associations by consensus.

Sperm motility by ING4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →