ING4

Across TCGA pan-cancer cohorts, ING4 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ING4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ING4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ING4 is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KIRC, KICH, and LIHC are the cancer types where ING4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ING4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.310	<.001	10	view →
KICH	Female	All	−1.350	<.001	7	view →
LIHC	Female	All	+0.730	<.001	7	view →
LUAD	Female	III,IV	−0.883	<.001	6	view →
UCEC	All	All	−0.563	.002	6	view →
CHOL	All	All	+1.987	<.001	5	view →
BRCA	Female	All	−0.176	.024	2	view →
LUSC	All	III,IV	−0.791	.031	1	view →
HNSC	Female	All	+0.400	.048	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ING4–KIRC

Open the KIRC breakdown →