ING3

Across TCGA patient cohorts, ING3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,953 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ING3-associated genes across cancer lineages are YPEL1, LMNB1, and POLA2. Each is linked with ING3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ING3-to-partner and partner-to-ING3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ING3 versus YPEL1 in UCEC, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ING3→partner) and Y-score (partner→ING3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YPEL1 →	+0.629	+0.181	.009	.002	3	5
BRCA	LMNB1 →	+0.951	+0.281	<.001	<.001	3	4
GBM	POLA2 →	+0.446	+0.336	.002	.001	3	4
BRCA	TONSL →	+1.069	+0.309	<.001	<.001	3	4
UCEC	VPS72 →	+0.822	+0.162	.009	.008	3	4
BRCA	CIP2A →	+0.850	+0.233	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,953 associations by consensus.

ING3 vs YPEL1 — UCEC

Explore this scatter interactively →