Across TCGA cell cohorts, INF2 mutation is significantly associated with the RNA expression of many other genes, with 1,840 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INF2-associated genes across cancer lineages are MREG, RPL22L1, and UST. Each is linked with INF2 in more than 3 cancer types. Because this analysis shows association rather than direction, both INF2-to-partner and partner-to-INF2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INF2→partner) and Y-score (partner→INF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MREG →	+0.650	+3.526	<.001	<.001	2	4
LARGE_INTESTINE	RPL22L1 →	+1.594	+3.584	<.001	<.001	3	3
BLOOD_Leukemia	UST →	+1.310	+3.199	<.001	.007	3	2
BLOOD_Leukemia	CAMK2N2 →	+0.821	+3.199	<.001	.007	3	2
BLOOD_Leukemia	SLC39A9 →	+0.710	+3.199	<.001	.007	3	2
LARGE_INTESTINE	MRPS10 →	+0.440	+3.850	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,840 associations by consensus.

Exploration

INF2 survival (RNA) · tumor vs normal (RNA) · all INF2 data types