INCENP

Across TCGA cell cohorts, INCENP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,263 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INCENP-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Mitotic nuclear division, and Regulation of cell cycle checkpoint. Each is linked with INCENP in more than 19 cancer types. Because this analysis shows association rather than direction, both INCENP-to-partner and partner-to-INCENP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by INCENP-low versus INCENP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INCENP→partner) and Y-score (partner→INCENP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cell cycle process →	+0.104	+1.607	<.001	<.001	3	20
BONE	Mitotic nuclear division →	+0.144	+1.527	.001	.001	3	20
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle checkpoint →	+0.103	+1.050	.001	.003	3	20
BONE	Negative regulation of cell cycle phase transition →	+0.075	+1.312	.004	<.001	3	20
BONE	Regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.223	+1.446	<.001	.002	3	20
BONE	Positive regulation of attachment of mitotic spindle microtubules to kinetochore →	+0.243	+1.567	<.001	.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,263 associations by consensus.

Negative regulation of cell cycle process by INCENP expression — BONE

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