INCENP

Across TCGA cell cohorts, INCENP mutation is significantly associated with the RNA expression of many other genes, with 280 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INCENP-associated genes across cancer lineages are IFNA2, CNTLN, and OR56A4. Each is linked with INCENP in more than 1 cancer types. Because this analysis shows association rather than direction, both INCENP-to-partner and partner-to-INCENP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA2 grouped by INCENP-low versus INCENP-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INCENP→partner) and Y-score (partner→INCENP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IFNA2 →	+0.036	+5.169	<.001	.005	3	2
LARGE_INTESTINE	CNTLN →	+1.111	+3.364	<.001	.002	3	2
BLOOD_Lymphoma	OR56A4 →	+0.054	+3.342	<.001	.008	3	2
BLOOD_Leukemia	MRPS18C →	+0.500	+3.259	.002	.006	3	2
BLOOD_Leukemia	WFDC10A →	+0.012	+3.569	<.001	.009	3	2
BLOOD_Leukemia	PPIE →	+0.660	+3.199	.002	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 280 associations by consensus.

IFNA2 by INCENP expression — BREAST

Explore this box plot interactively →