INA

Across TCGA patient cohorts, INA protein abundance is significantly associated with the RNA expression of many other genes, with 6,467 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INA-associated genes across cancer lineages are ELAVL3, SOX10, and NEFH. Each is linked with INA in more than 3 cancer types. Because this analysis shows association rather than direction, both INA-to-partner and partner-to-INA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INA versus ELAVL3 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INA→partner) and Y-score (partner→INA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ELAVL3 →	+1.123	+0.997	<.001	<.001	3	4
GBM	SOX10 →	+1.734	+1.088	<.001	<.001	3	3
GBM	NEFH →	+1.089	+0.848	<.001	<.001	3	3
GBM	SYP →	+1.153	+0.755	<.001	<.001	3	3
COAD	PCSK1N →	+1.383	+0.645	<.001	<.001	3	3
COAD	SFRP1 →	+1.393	+0.570	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,467 associations by consensus.

INA vs ELAVL3 — GBM

Explore this scatter interactively →