Across TCGA pan-cancer cohorts, IMPDH1P7 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated IMPDH1P7 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher IMPDH1P7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IMPDH1P7 expression acts as an unfavorable survival marker, although some lineages such as OV and UCEC show a favorable association.

LIHC, OV, and KIRC are the cancer types where IMPDH1P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.433	0.667	<.001	69	view →
OV	DFS	Tertile	All	0.620	0.492	.001	64	view →
KIRC	DFS	Tertile	IV	0.401	0.691	.001	36	view →
UCS	DFS	Median	IV	0.367	0.952	.001	36	view →
UCEC	DFS	Median	IV	0.906	0.508	.015	36	view →
KIRP	DFS	Tertile	All	0.524	0.880	.003	24	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
LGG	OS	Tertile	All	0.590	0.864	<.001	18	view →
COAD	DFS	Quartile	All	0.778	0.650	.013	17	view →
BRCA	DFS	Quartile	All	0.858	0.912	.019	16	view →
UVM	DFS	Quartile	III,IV	0.339	0.761	.016	9	view →
THCA	DFS	Tertile	IV	0.126	0.805	.002	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

Exploration

Same gene, other analysis: IMPDH1P7 tumor-vs-normal RNA expression · all IMPDH1P7 data types