Q-omics provides the consensus-scored IMPDH1P7 profile across patient tissues and cancer cell-line models. IMPDH1P7 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, IMPDH1P7 is differentially expressed in 4, with the highest sampling consensus in COAD. Additionally, IMPDH1P7 RNA expression shows 6,665 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight LIHC, COAD, and TGCT as cancer lineages where IMPDH1P7 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for IMPDH1P7 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes IMPDH1P7 survival associations across molecular data types. IMPDH1P7 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible IMPDH1P7 RNA expression–survival associations across cancer types. High IMPDH1P7 expression shows unfavorable associations in LIHC, UCS, KIRC and KIRP, but favorable associations in OV and UCEC. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for IMPDH1P7 RNA expression.
This table summarizes IMPDH1P7 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for IMPDH1P7. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. IMPDH1P7 shows higher tumor expression in COAD, UCEC, PRAD and LIHC. The COAD box plot shows higher IMPDH1P7 RNA expression in tumor versus normal tissue (log2 FC = +0.075, t-test p = .007).
This table shows molecular features associated with IMPDH1P7 in patient tissues and cancer cell lines. In patient samples, IMPDH1P7 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
