IMP3

Across TCGA patient cohorts, IMP3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,481 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IMP3-associated genes across cancer lineages are SNHG4, FAM136A, and EIF2B4. Each is linked with IMP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both IMP3-to-partner and partner-to-IMP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IMP3 versus SNHG4 in LSCC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IMP3→partner) and Y-score (partner→IMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SNHG4 →	+0.997	+0.412	<.001	<.001	3	7
LSCC	FAM136A →	+0.728	+0.424	<.001	<.001	3	7
LSCC	EIF2B4 →	+0.434	+0.355	<.001	<.001	3	6
UCEC	RPS10 →	+0.562	+0.282	<.001	.003	3	6
BRCA	MYC →	+1.046	+0.349	<.001	.001	3	6
BRCA	TAF4B →	+1.146	+0.397	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,481 associations by consensus.

IMP3 vs SNHG4 — LSCC

Explore this scatter interactively →