ILVBL

Across TCGA patient cohorts, ILVBL mutation is significantly associated with the RNA expression of many other genes, with 1,638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILVBL-associated genes across cancer lineages are RRM2, BNIP1, and IER3IP1. Each is linked with ILVBL in more than 2 cancer types. Because this analysis shows association rather than direction, both ILVBL-to-partner and partner-to-ILVBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RRM2 grouped by ILVBL-low versus ILVBL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILVBL→partner) and Y-score (partner→ILVBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.624	+1.773	.003	.008	3	3
UCEC	BNIP1 →	+0.305	+2.136	<.001	.002	3	3
UCEC	IER3IP1 →	+0.363	+2.141	.005	.002	3	3
UCEC	GTF2A2 →	+0.339	+1.872	.008	.004	3	3
BRCA	MIR6894 →	+0.541	+5.506	<.001	.005	3	2
READ	LINC00458 →	+0.020	+5.039	.005	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,638 associations by consensus.

RRM2 by ILVBL expression — UCEC

Explore this box plot interactively →