ILVBL

Across TCGA pan-cancer cohorts, ILVBL RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ILVBL’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where ILVBL RNA is repressed in tumor relative to normal tissue. In most cancer types ILVBL is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, BLCA, and COAD are the cancer types where ILVBL tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ILVBL RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	IV	−1.240	<.001	9	view →
BLCA	Male	All	+0.593	.014	8	view →
COAD	All	All	+0.334	.002	5	view →
LUSC	All	All	+0.314	<.001	5	view →
LIHC	All	All	+0.404	<.001	4	view →
KIRC	Male	All	−0.303	.007	4	view →
CHOL	Female	All	+0.719	.005	2	view →
PRAD	All	All	−0.585	<.001	2	view →
KIRP	Male	All	−0.523	.003	2	view →
UCEC	All	II,III,IV	−0.372	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ILVBL–THCA

Open the THCA breakdown →