ILVBL

Across TCGA patient cohorts, ILVBL mutation is significantly associated with the total protein of many other genes, with 30 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILVBL-associated genes across cancer lineages are ERK2, GAPDH, and PCNA. Each is linked with ILVBL in more than 1 cancer types. Because this analysis shows association rather than direction, both ILVBL-to-partner and partner-to-ILVBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by ILVBL-low versus ILVBL-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILVBL→partner) and Y-score (partner→ILVBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ERK2 →	+0.253	+2.832	.017	.035	3	2
COAD	GAPDH →	+0.855	+2.815	.002	.036	3	2
COAD	PCNA →	+0.374	+2.820	.005	.035	3	2
UCEC	MSH2 →	-0.240	-2.196	.003	.009	3	2
UCEC	PDCD4 →	-0.447	-1.925	.008	.005	3	2
UCEC	Rab25 →	-0.253	-1.874	.034	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

ERK2 by ILVBL expression — COAD

Explore this box plot interactively →