ILVBL

Across TCGA cell cohorts, ILVBL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,282 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ILVBL-associated GO terms across cancer lineages are Regulation of anaphase-promoting complex-dependent catabolic process, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Negative regulation of protein localization to chromatin. Each is linked with ILVBL in more than 11 cancer types. Because this analysis shows association rather than direction, both ILVBL-to-partner and partner-to-ILVBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of anaphase-promoting complex-dependent catabolic process grouped by ILVBL-low versus ILVBL-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ILVBL→partner) and Y-score (partner→ILVBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.156	+0.547	<.001	<.001	3	12
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.159	+0.643	<.001	<.001	3	12
BONE	Negative regulation of protein localization to chromatin →	+0.139	+0.568	.001	.001	3	11
BONE	Mitochondrial tRNA wobble uridine modification →	+0.155	+0.554	.006	.002	3	9
BONE	Transcription pausing by RNA polymerase II →	+0.165	+0.632	<.001	<.001	3	9
BONE	Positive regulation of T-helper 17 cell lineage commitment →	+0.167	+0.704	.003	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,282 associations by consensus.

Regulation of anaphase-promoting complex-dependent catabolic process by ILVBL expression — BONE

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