ILVBL

Across TCGA cell cohorts, ILVBL mutation is significantly associated with the RNA expression of many other genes, with 575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ILVBL-associated genes across cancer lineages are METTL11B, PRAMEF18, and GZMK. Each is linked with ILVBL in more than 1 cancer types. Because this analysis shows association rather than direction, both ILVBL-to-partner and partner-to-ILVBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, METTL11B grouped by ILVBL-low versus ILVBL-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILVBL→partner) and Y-score (partner→ILVBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	METTL11B →	+0.135	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	PRAMEF18 →	+0.004	+4.643	<.001	.005	3	1
BLOOD_Leukemia	GZMK →	+0.416	+4.037	.008	.004	3	1
BLOOD_Leukemia	VSX2 →	+0.032	+4.258	<.001	.002	3	1
BLOOD_Leukemia	CST8 →	+0.037	+4.384	<.001	.006	3	1
BLOOD_Leukemia	SOX14 →	+0.005	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 575 associations by consensus.

METTL11B by ILVBL expression — BLOOD_Lymphoma

Explore this box plot interactively →