Across TCGA patient cohorts, ILRUN mutation is significantly associated with the RNA expression of many other genes, with 867 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILRUN-associated genes across cancer lineages are IGKV2OR2-1, IGHV3OR16-8, and MAP3K4-AS1. Each is linked with ILRUN in more than 1 cancer types. Because this analysis shows association rather than direction, both ILRUN-to-partner and partner-to-ILRUN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILRUN→partner) and Y-score (partner→ILRUN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGKV2OR2-1 →	+0.439	+2.367	.003	.002	3	1
UCEC	IGHV3OR16-8 →	+0.750	+3.721	.002	<.001	3	1
UCEC	MAP3K4-AS1 →	+1.047	+3.700	<.001	.001	3	1
UCEC	CYFIP1 →	+0.601	+2.617	.003	.006	3	1
UCEC	RNA5SP414 →	+0.779	+2.407	<.001	.006	3	1
UCEC	MIR7702 →	+0.263	+4.475	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 867 associations by consensus.

Exploration

ILRUN survival (RNA) · tumor vs normal (RNA) · all ILRUN data types