ILK

Across TCGA patient cohorts, ILK protein abundance is significantly associated with the protein abundance of many other proteins, with 36,385 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ILK-associated proteins across cancer lineages are HIC1_S313, HSPG2, and IGFBP7. Each is linked with ILK in more than 9 cancer types. Because this analysis shows association rather than direction, both ILK-to-partner and partner-to-ILK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ILK versus HIC1_S313 in PDAC, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ILK→partner) and Y-score (partner→ILK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HIC1_S313 →	+0.796	+0.309	<.001	<.001	3	10
OV	HSPG2 →	+0.710	+0.469	<.001	<.001	3	10
GBM	IGFBP7 →	+0.709	+0.278	<.001	<.001	3	10
UCEC	ARHGEF17 →	+0.515	+0.691	<.001	<.001	3	10
OV	ASPN →	+1.268	+0.465	<.001	<.001	3	10
COAD	ACTN1 →	+0.808	+0.667	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 36,385 associations by consensus.

ILK vs HIC1_S313 — PDAC

Explore this scatter interactively →