ILDR2

Across TCGA patient cohorts, ILDR2 mutation is significantly associated with the RNA expression of many other genes, with 2,942 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ILDR2-associated genes across cancer lineages are RNU1-6P, RN7SL817P, and WDR62. Each is linked with ILDR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both ILDR2-to-partner and partner-to-ILDR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-6P grouped by ILDR2-low versus ILDR2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ILDR2→partner) and Y-score (partner→ILDR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU1-6P →	+0.342	+2.892	<.001	.002	3	4
LUSC	RN7SL817P →	+0.293	+3.980	<.001	<.001	3	3
UCEC	WDR62 →	+0.711	+3.928	<.001	<.001	3	3
UCEC	CEP57L1 →	+0.397	+3.023	.002	<.001	3	3
UCEC	ARHGAP11A →	+0.688	+1.858	.001	.005	3	3
COAD	OR2F1 →	+0.061	+3.917	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,942 associations by consensus.

RNU1-6P by ILDR2 expression — LUAD

Explore this box plot interactively →