IL9R

Across TCGA pan-cancer cohorts, IL9R mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated IL9R data layer compared with 18 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher IL9R mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated IL9R expression acts as an unfavorable survival marker, although some lineages such as GBM and LUAD show a favorable association.

PDAC, GBM, and LUAD are the cancer types where IL9R mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	II,III,IV	0.286	1.000	.010	24	view →
GBM	OS	Tertile	All	1.000	0.836	.007	8	view →
LUAD	OS	Quartile	All	1.000	0.314	.031	4	view →
CCRCC	DFS	Median	III,IV	0.485	1.000	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

IL9R–PDAC (OS)

Open the PDAC breakdown →