IL9R

Across TCGA patient cohorts, IL9R mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL9R-associated genes across cancer lineages are Tuberin_pT1462, ASNS, and FOXO3a_pS318_S321. Each is linked with IL9R in more than 1 cancer types. Because this analysis shows association rather than direction, both IL9R-to-partner and partner-to-IL9R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tuberin_pT1462 grouped by IL9R-low versus IL9R-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL9R→partner) and Y-score (partner→IL9R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Tuberin_pT1462 →	+0.310	+1.710	.001	.025	3	2
UCEC	ASNS →	+0.533	+3.459	<.001	.005	3	2
SKCM	FOXO3a_pS318_S321 →	+0.135	+2.334	.026	.018	3	1
UCEC	JNK2 →	+0.279	+2.321	<.001	.006	2	2
UCEC	14-3-3_beta →	-0.115	-3.143	.005	.018	3	1
UCEC	eIF4E →	+0.265	+3.000	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Tuberin_pT1462 by IL9R expression — UCEC

Explore this box plot interactively →