IL9R

Across TCGA cell cohorts, IL9R RNA expression is significantly associated with the go_rna of many other GO terms, with 3,066 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL9R-associated GO terms across cancer lineages are Negative regulation of mRNA processing, B cell mediated immunity, and Nucleic acid catabolic process. Each is linked with IL9R in more than 9 cancer types. Because this analysis shows association rather than direction, both IL9R-to-partner and partner-to-IL9R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA processing grouped by IL9R-low versus IL9R-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL9R→partner) and Y-score (partner→IL9R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of mRNA processing →	+0.092	+0.334	<.001	<.001	3	10
SOFT_TISSUE	B cell mediated immunity →	-0.122	-0.191	<.001	<.001	3	9
OESOPHAGUS	Nucleic acid catabolic process →	+0.056	+0.493	.001	.003	3	9
OESOPHAGUS	Positive regulation of mRNA metabolic process →	+0.064	+0.527	<.001	<.001	3	9
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.092	+0.334	<.001	<.001	3	9
BONE	Metaphase/anaphase transition of mitotic cell cycle →	+0.157	+0.198	.005	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,066 associations by consensus.

Negative regulation of mRNA processing by IL9R expression — BONE

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