IL6R

Across TCGA patient cohorts, IL6R protein abundance is significantly associated with the RNA expression of many other genes, with 1,992 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL6R-associated genes across cancer lineages are RNU6-353P, HCAR3, and CTSH. Each is linked with IL6R in more than 1 cancer types. Because this analysis shows association rather than direction, both IL6R-to-partner and partner-to-IL6R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL6R versus RNU6-353P in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL6R→partner) and Y-score (partner→IL6R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU6-353P →	+1.049	+0.992	.002	.002	3	2
PDAC	HCAR3 →	+1.270	+0.939	.009	.004	3	2
LUAD	CTSH →	+1.125	+0.482	.002	.001	3	2
GBM	ABI3BP →	+1.503	+1.262	.001	<.001	3	2
LUAD	SCARA5 →	+1.783	+0.604	<.001	<.001	3	2
LUAD	CHRNA5 →	-1.184	-0.559	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,992 associations by consensus.

IL6R vs RNU6-353P — GBM

Explore this scatter interactively →