IL4R

Across TCGA patient cohorts, IL4R protein abundance is significantly associated with the RNA expression of many other genes, with 11,526 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IL4R-associated genes across cancer lineages are DYRK1B, SCN1B, and SMG9. Each is linked with IL4R in more than 1 cancer types. Because this analysis shows association rather than direction, both IL4R-to-partner and partner-to-IL4R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL4R versus DYRK1B in LUAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL4R→partner) and Y-score (partner→IL4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DYRK1B →	+0.745	+0.596	.001	.005	3	1
LUAD	SCN1B →	+0.690	+0.625	.002	.003	3	1
LUAD	SMG9 →	+0.577	+0.644	<.001	.002	3	1
LUAD	GNB3 →	+0.528	+0.633	<.001	.002	3	1
LUAD	ATN1 →	+0.743	+0.625	.001	.003	3	1
LUAD	XRCC3 →	+0.513	+0.583	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,526 associations by consensus.

IL4R vs DYRK1B — LUAD

Explore this scatter interactively →