IL4I1

Across TCGA pan-cancer cohorts, IL4I1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated IL4I1 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher IL4I1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated IL4I1 expression acts as an unfavorable survival marker.

COAD, CCRCC, and GBM are the cancer types where IL4I1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	III,IV	0.736	1.000	.010	114	view →
CCRCC	OS	Median	All	0.740	0.951	.003	43	view →
GBM	OS	Median	All	0.276	0.545	.007	6	view →
LSCC	DFS	Tertile	II,III,IV	0.519	0.843	.027	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

IL4I1–COAD (DFS)

Open the COAD breakdown →