IL4I1

Across TCGA cell cohorts, IL4I1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,351 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IL4I1-associated GO terms across cancer lineages are Positive regulation of protein modification by small protein conjugation or removal, Regulation of response to cytokine stimulus, and Positive regulation of post-translational protein modification. Each is linked with IL4I1 in more than 12 cancer types. Because this analysis shows association rather than direction, both IL4I1-to-partner and partner-to-IL4I1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein modification by small protein conjugation or removal grouped by IL4I1-low versus IL4I1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL4I1→partner) and Y-score (partner→IL4I1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of protein modification by small protein conjugation or removal →	+0.071	+0.835	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of response to cytokine stimulus →	+0.096	+0.862	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of post-translational protein modification →	+0.073	+0.848	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of type I interferon production →	+0.070	+0.695	<.001	.003	3	12
SOFT_TISSUE	Positive regulation of canonical NF-kappaB signal transduction →	+0.088	+1.598	<.001	<.001	3	12
SOFT_TISSUE	Regulation of cytokine-mediated signaling pathway →	+0.093	+1.286	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,351 associations by consensus.

Positive regulation of protein modification by small protein conjugation or removal by IL4I1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →