Across TCGA patient cohorts, IL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,089 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IL4-associated GO terms across cancer lineages are Obsolete ncRNA export from nucleus, Negative regulation of cellular response to transforming growth factor beta stimulus, and Obsolete regulation of dosage compensation by inactivation of X chromosome. Each is linked with IL4 in more than 24 cancer types. Because this analysis shows association rather than direction, both IL4-to-partner and partner-to-IL4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL4→partner) and Y-score (partner→IL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Obsolete ncRNA export from nucleus →	+0.060	+0.254	<.001	<.001	3	25
LAML	Negative regulation of cellular response to transforming growth factor beta stimulus →	-0.104	-0.294	<.001	<.001	3	24
STAD	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.067	+0.143	<.001	<.001	3	23
STAD	Obsolete regulation of histone modification →	+0.054	+0.166	<.001	<.001	3	23
STAD	Positive regulation of DNA repair →	+0.048	+0.164	<.001	<.001	3	23
STAD	Positive regulation of transcription elongation by RNA polymerase II →	+0.056	+0.154	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,089 associations by consensus.

Exploration

IL4 survival (RNA) · tumor vs normal (RNA) · all IL4 data types