IL4

Across TCGA patient cohorts, IL4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,060 significant associations in total. COAD shows the largest number of these associations.

The most reproducible IL4-associated genes across cancer lineages are C20orf27, RRP8, and MOB2. Each is linked with IL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both IL4-to-partner and partner-to-IL4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL4 versus C20orf27 in OV, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL4→partner) and Y-score (partner→IL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C20orf27 →	-0.579	-0.630	.006	.004	3	2
OV	RRP8 →	-0.469	-0.650	.004	.001	3	2
OV	MOB2 →	-0.564	-0.595	.002	.003	3	2
PDAC	LINC02030 →	+0.069	+0.344	.001	.001	3	2
COAD	NUCB2 →	+1.113	+0.342	.001	.006	3	2
HNSC	FAM117A →	-0.589	-0.359	.007	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,060 associations by consensus.

IL4 vs C20orf27 — OV

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