IL4

Across TCGA patient cohorts, IL4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IL4-associated genes across cancer lineages are Adipocytes, pDC, and mv Endothelial cells. Each is linked with IL4 in more than 1 cancer types. Because this analysis shows association rather than direction, both IL4-to-partner and partner-to-IL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by IL4-low versus IL4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL4→partner) and Y-score (partner→IL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Adipocytes →	+0.028	+2.144	.003	.036	3	1
UCEC	pDC →	+0.062	+3.180	.019	.010	3	1
UCEC	mv Endothelial cells →	-0.027	-3.159	.034	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by IL4 expression — UCEC

Explore this box plot interactively →